One liners from Sheen's Roast....
"I have to say, Charlie, you are an incredible medical specimen," said Kate Walsh. "I guess that's one of the benefits of waking up every morning at the crack of crack."
80-year-old William Shatner asked Charlie, 46, "How come we look like we went to high school together?".
"Charlie don't you want to live to see [your kids'] first 12 steps," said Jeffrey Ross.
"It was international news when he ruined the lives of those two girls living with [him] ... you know, [his] daughters," joked Amy Schumer.